Intracellular organization of hippocampal neurons during the development of neuronal polarity.

  title={Intracellular organization of hippocampal neurons during the development of neuronal polarity.},
  author={Carlos G Dotti and Gary A. Banker},
  journal={Journal of cell science. Supplement},
In culture, hippocampal neurons initially establish several short, apparently identical processes; of these, only one acquires axonal characteristics, the remainder becoming dendrites. We examined the organization of cytoplasmic constituents that might influence which of the initial processes becomes the axon. The Golgi complex was visualized using either fluorescent wheat germ agglutinin or a specific antibody. Presumptive microtubule-organizing centers were identified by depolymerizing… CONTINUE READING
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