Intracellular monocyte cytokine production and CD 14 expression are up-regulated in severe vs mild chronic heart failure.


BACKGROUND The role of circulating monocytes in the process of low-grade inflammation, characteristic of chronic heart failure (CHF), has recently been questioned. Lipopolysaccharide (LPS) desensitization has been proposed to mediate reduced monocyte cytokine elaboration in patients with severe CHF. METHODS Intracellular monocyte production of interleukin… (More)


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