Intracellular mobility of plasmid DNA is limited by the ParA family of partitioning systems.

@article{Derman2008IntracellularMO,
  title={Intracellular mobility of plasmid DNA is limited by the ParA family of partitioning systems.},
  author={Alan I. Derman and Grace E. Lim-Fong and Joe Pogliano},
  journal={Molecular microbiology},
  year={2008},
  volume={67 5},
  pages={935-46}
}
The highly conserved ParA family of partitioning systems is responsible for positioning DNA and protein complexes in bacteria. In Escherichia coli, plasmids that rely upon these systems are positioned at mid-cell and are repositioned at the quarter-cell positions after replication. How they remain fixed at these positions throughout the cell cycle is unknown. We use fluorescence recovery after photobleaching and time-lapse microscopy to measure plasmid mobility in living E. coli cells. We find… CONTINUE READING

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