Intracellular mediators of erucylphosphocholine-induced apoptosis

@article{Jendrossek2003IntracellularMO,
  title={Intracellular mediators of erucylphosphocholine-induced apoptosis},
  author={Verena Jendrossek and Ilka M{\"u}ller and Hansj{\"o}rg Prof. Dr. Eibl and Claus Belka},
  journal={Oncogene},
  year={2003},
  volume={22},
  pages={2621-2631}
}
Induction of apoptosis contributes to the cytotoxic action of the intravenously applicable alkylphosphocholine erucylphosphocholine (ErPC). To define molecular requirements for ErPC-induced apoptosis, activation of caspases-8, -9 and -3 and cleavage of the caspase-3 substrates PARP and ICAD were tested in normal Jurkat T cells, Jurkat cells resistant to death receptor (CD95 or TNFα-related apoptosis inducing ligand (TRAIL)-induced apoptosis, Jurkat cells lacking caspase-8 or Fas-associated… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 26 CITATIONS