Intracellular magnesium and magnesium buffering

  title={Intracellular magnesium and magnesium buffering},
  author={Robert D. Grubbs},
  • R. Grubbs
  • Published 1 September 2002
  • Biology
  • Biometals
The development of new techniques for measuring intracellular free Mg2+ during the 1980s has provided investigators with the tools needed to produce new insights into the regulation of cellular magnesium. Within the limits of this technology, it appears that all mammalian cells maintain free cytosolic Mg2+ levels within the fairly narrow range of 0.25–1 mM. While transport mechanisms and sequestration within cellular organelles will contribute to this regulation, it is binding of Mg2+ to an as… 
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  • E. Murphy
  • Medicine
    Mineral and electrolyte metabolism
  • 1993
If one needs to accurately know Mgi in a papillary muscle or some other tissue which is readily impaled then ion-selective microelectrodes may be the method of choice.
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