Intracellular localization of the SARS coronavirus protein 9b: evidence of active export from the nucleus.

@article{Moshynskyy2007IntracellularLO,
  title={Intracellular localization of the SARS coronavirus protein 9b: evidence of active export from the nucleus.},
  author={Igor D Moshynskyy and Sathiyanarayanan Viswanathan and Natalia Vasilenko and Vladislav A. Lobanov and Martin Petric and Lorne A. Babiuk and Alexander N. Zakhartchouk},
  journal={Virus research},
  year={2007},
  volume={127 1},
  pages={116-21}
}
Open reading frame 9b (ORF 9b) encodes a 98 amino acid group-specific protein of severe acute respiratory syndrome (SARS) coronavirus (CoV). It has no homology with known proteins and its function in SARS CoV replication has not been determined. The N-terminal part of the 9b protein was used to raise polyclonal antibodies in rabbits, and these antibodies could detect 9b protein in infected cells. We analyzed the sub-cellular localization of recombinant 9b protein using fluorescence microscopy… CONTINUE READING