Intracellular localization of secretable cAMP in relaying Dictyostelium discoideum cells.

@article{Schoen1989IntracellularLO,
  title={Intracellular localization of secretable cAMP in relaying Dictyostelium discoideum cells.},
  author={Cor D. Schoen and Jos C. Arents and Taco Bruin and Roel van Driel},
  journal={Experimental cell research},
  year={1989},
  volume={181 1},
  pages={51-62}
}
Dictyostelium discoideum cells synthesize and secrete the chemoattractant cAMP within minutes after chemotactic stimulation. During development, this signal-relay process is instrumental in cell aggregation, pattern formation, and differentiation. Cyclic AMP is known to accumulate inside the cell before secretion. In this study we investigated the… CONTINUE READING