Intracellular localization and unique conserved sequences of three small nucleolar RNAs.

@article{Selvamurugan1997IntracellularLA,
  title={Intracellular localization and unique conserved sequences of three small nucleolar RNAs.},
  author={Nagarajan Selvamurugan and Oscar Joost and Elizabeth S. Haas and John W. S. Brown and Nancy J. Galvin and George L. Eliceiri},
  journal={Nucleic acids research},
  year={1997},
  volume={25 8},
  pages={1591-6}
}
Three human small nucleolar RNAs (snoRNAs), E1, E2 and E3, were reported earlier that have unique sequences, interact directly with unique segments of pre-rRNA in vivo and are encoded in introns of protein genes. In the present report, human and frog E1, E2 and E3 RNAs injected into the cytoplasm of frog oocytes migrated to the nucleus and specifically to the nucleolus. This indicates that the nucleolar and nuclear localization signals of these snoRNAs reside within their evolutionarily… CONTINUE READING