Intracellular localization and trafficking of steroid receptors

  title={Intracellular localization and trafficking of steroid receptors},
  author={Christopher T. Baumann and Carol S Lim and Gordon L. Hager},
  journal={Cell Biochemistry and Biophysics},
Steroid receptors are ligand-dependent transcription factors whose cellular functions are to regulate expression of their target genes in response to specific ligand agonists and antagonists (reviewed in ref. 1). Transcriptional regulation generally occurs through the recruitment of transacting proteins to the promoters of their target genes. These proteins include basal transcription factors (TFIID, TFIIB, and so on), receptor coactivators (i.e., SRC-la, glucocorticoid receptor-interacting… CONTINUE READING


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Proceedings of the National Academy of Sciences of the United States of America • 1998
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