Intracellular labeling of T-cells with superparamagnetic contrast agents.

@article{Yeh1993IntracellularLO,
  title={Intracellular labeling of T-cells with superparamagnetic contrast agents.},
  author={Tzu chen Yeh and Wei Zhang and SuzanneT. Ildstad and Calvin Wai Loon Ho},
  journal={Magnetic resonance in medicine},
  year={1993},
  volume={30 5},
  pages={
          617-25
        }
}
Isolated rat T-cells have been labeled intracellularly, using endocytosis uptake of two superparamagnetic contrast agents, AquaMag100 and BMS180549, which are both iron-oxide particles coated with dextran. No deterioration of cell proliferation response to mitogen stimulation was observed after labeling with either superparamagnetic contrast agent. AquaMag100 particles show aggregation and co-precipitation in culture media for T-cells. BMS180549 particles not only produce no observable… CONTINUE READING
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