Intracellular ion concentrations and their maintenance by Na+/K(+)-ATPase in preimplantation mouse embryos.

@article{Baltz1997IntracellularIC,
  title={Intracellular ion concentrations and their maintenance by Na+/K(+)-ATPase in preimplantation mouse embryos.},
  author={Jay M Baltz and S. A. Sweeney Smith and John D. Biggers and Claude P. Lechene},
  journal={Zygote},
  year={1997},
  volume={5 1},
  pages={1-9}
}
We have measured the amounts of Na+, K+ and C- in preimplantation mouse embryos (1-cell, 2-cell and morula) using electron probe X-ray microanalysis. The levels of these ions do not vary much over this period, and are approximately the same as those found in other mammalian cells, contrary to previous reports. We have confirmed that preimplantation embryos exhibit Na+/K(+)-ATPase activity at all stages examined, and have shown that the ATPase maintains high K+/Na+ ratios (12-16) in all these… CONTINUE READING

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