[Intracellular hormonal function of acetylcholine and noradrenaline: the regulation of the catalase level in liver cells].

Abstract

The injection of acetylcholine (15 to 150 micrograms/100 g) to rats or preincubation in the hepatic homogenate with acetylcholine (10(-6) to 10(-3) M) induces a decrease in the catalase activity, mainly in its bound form. Acetylcholine effect does not manifest in the presence of actinomycine D and puromycine. Noradrenaline injection to animals (1.5 to 15 micrograms/100 g) or preincubation of the hepatic homogenate with noradrenaline (10(-6) to 10(-3) M) produces a rise of the catalase activity (mainly of its bound form), being blocked by actinomycine D and non-blocked by propranolol. Acetylcholine- and noradrenaline action on the catalase level is not mediated by cyclic nucleotides and may be considered as intracellular hormonal effect.

Cite this paper

@article{Elaev1984IntracellularHF, title={[Intracellular hormonal function of acetylcholine and noradrenaline: the regulation of the catalase level in liver cells].}, author={N. R. Elaev and M K Panova and Ekaterina V. Mikhailova and N. V. Kharitonova}, journal={Problemy ėndokrinologii}, year={1984}, volume={30 3}, pages={69-72} }