Intracellular folate distribution in cultured fibroblasts from patients with the fragile X syndrome.

Abstract

Altered folate metabolism has been suggested as a possible reason for expression of the fragile X chromosome in low-folate medium. However, there were no significant differences in the total folate content or in the distribution of folate cofactors between fibroblasts from patients with the fragile X chromosome and those of controls both before and after a… (More)

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