Intracellular events and signaling pathways involved in sperm acquisition of fertilizing capacity and acrosome reaction.

@article{Baldi2000IntracellularEA,
  title={Intracellular events and signaling pathways involved in sperm acquisition of fertilizing capacity and acrosome reaction.},
  author={Elizabetta Baldi and Michaela Luconi and Lorella Bonaccorsi and Monica Muratori and Gianni Forti},
  journal={Frontiers in bioscience : a journal and virtual library},
  year={2000},
  volume={5},
  pages={E110-23}
}
Two processes, namely capacitation and acrosome reaction, are of fundamental importance in the fertilization of oocyte by spermatozoon. Physiologically occurring in the female genital tract, capacitation is a complex process, which renders the sperm cell capable for specific interaction with the oocyte. During capacitation, modification of membrane characteristics, enzyme activity and motility properties of spermatozoa render these cells able to penetrate oocyte investments and responsive to… CONTINUE READING