Intracellular distribution and functional importance of vesicle-associated membrane protein 2 in gastric parietal cells.

@article{Karvar2002IntracellularDA,
  title={Intracellular distribution and functional importance of vesicle-associated membrane protein 2 in gastric parietal cells.},
  author={Serhan Karvar and Xuebiao Yao and Joseph G. Duman and Kevin Hybiske and Yuechueng Liu and John G. Forte},
  journal={Gastroenterology},
  year={2002},
  volume={123 1},
  pages={281-90}
}
BACKGROUND & AIMS Acid secretion by parietal cells involves secretagogue-dependent recycling of the H+-K+-ATPase. Proteins called soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) have been implicated as participants in membrane trafficking, docking, and fusing processes. Here we studied the intracellular distribution and functional importance of one SNARE protein, vesicle associated membrane protein-2 (VAMP-2), in gastric parietal cells. METHODS Using an… CONTINUE READING

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