Intracellular cytokine repertoire in different T cell subsets from patients with sarcoidosis.

@article{Moellers2001IntracellularCR,
  title={Intracellular cytokine repertoire in different T cell subsets from patients with sarcoidosis.},
  author={M Moellers and S. P. Aries and Daniel Dr{\"o}mann and Beate Mascher and Jorg Braun and Klaus Dalhoff},
  journal={Thorax},
  year={2001},
  volume={56 6},
  pages={487-93}
}
BACKGROUND Pulmonary sarcoidosis is characterised by a mononuclear alveolitis with a predominance of CD4+ T cells and macrophages. We determined the intracellular expression of interferon (IFN)gamma, interleukin (IL)-2, tumour necrosis factor (TNF)alpha, IL-4, IL-5 and IL-10 in CD4+ and CD8+, naive and memory lymphocytes from blood and bronchoalveolar lavage (BAL) fluid using three colour flow cytometry. METHODS Eighteen untreated patients with pulmonary sarcoidosis were evaluated and… CONTINUE READING