Intracellular currents of interictal penicillin spikes: Evidence from neuromagnetic mapping

  title={Intracellular currents of interictal penicillin spikes: Evidence from neuromagnetic mapping},
  author={Daniel S. Barth and William Sutherling and Jackson Beatty},
  journal={Brain Research},
Empirical comparison of the MEG and EEG: Animal models of the direct cortical response and epileptiform activity in neocortex
The data support the hypothesis that evoked and epileptiform magnetic fields result from intradendritic currents oriented perpendicular to the cortical surface, and provide an empirical foundation for physical models with which to interpret noninvasive neuromagnetic recordings of epileptic discharge in human focal seizure disorders.
Neuromagnetic investigation of somatotopy of human hand somatosensory cortex
It is concluded that SEFs recorded on MEG in conjunction with source localization techniques are useful to investigate functional topography of human hand somatosensory cortex non-invasively.
The relationship between magnetic and electrophysiological responses to complex tactile stimuli
The MEG signal is an accurate representation of electrophysiological responses to complex natural stimuli and was better correlated with the LFP than MUA data suggesting that the MEG signals reflects primarily synaptic currents rather than spiking activity.
Magnetoencephalography in presurgical epilepsy evaluation
Because MEG and EEG yield both complementary and confirmatory information, combined MEG-EEG recordings in conjunction with advanced source modeling techniques will further improve the noninvasive evaluation of epilepsy patients and constantly reduce the need for invasive procedures.
In Vivo Neuromagnetic Study of Normal and Pathological Intracellular Current in Rat Cortex
The magnetoencephalogram may be used to localize and study synchronized cellular currents during physiological and pathological cortical activities in animal and man, and may provide valuable information for understanding the neurogenesis of cortical responses.


Electrical sources in human somatosensory cortex: identification by combined magnetic and potential recordings.
Fields and potentials occurring 20 to 30 milliseconds after median nerve stimulation in human subjects were compared in order to investigate the sources of evoked potential components that have been attributed by different investigators to the thalamus or thalamocortical afferents, to separate radial sources in somatosensory cortex and motor cortex, or to a tangential source in somatic cortex.
Control mechanisms in cortical epileptogenic foci. "Surround" inhibition.
The role of inhibited neurons in a region of focal epileptogenesis and the relationship of such cells to the neuronal population responsible for generation of the surface epileptiform activity is investigated.
The penicillin focus. I. Distribution of potential at the cortical surface.
Neuromagnetic localization of epileptiform spike activity in the human brain.
Local paroxysmal discharges of epileptic tissue within the human brain also generate extracranial magnetic fields, which were assessed by means of recently developed neuromagnetometric techniques.
Metabolic anatomy of focal motor seizures.
The anatomic dimensions of the metabolic response in the focus as well as the spread of increased activity through the brain were studied by autoradiography following intravenous injection of carbon 14-labeled 2-deoxyglucose.
Neuromagnetic evidence of spatially distributed sources underlying epileptiform spikes in the human brain.
Neuromagnetic measurements were performed on 17 subjects with focal seizure disorders. In all of the subjects, the interictal spike in the scalp electroencephalogram was associated with an orderly