Intracellular currents of interictal penicillin spikes: Evidence from neuromagnetic mapping

@article{Barth1986IntracellularCO,
  title={Intracellular currents of interictal penicillin spikes: Evidence from neuromagnetic mapping},
  author={Daniel S. Barth and William Sutherling and Jackson Beatty},
  journal={Brain Research},
  year={1986},
  volume={368},
  pages={36-48}
}
View on Elsevier
doi.org
34 Citations
Background Citations
8
Methods Citations
1

34 Citations

Current source-density and neuromagnetic analysis of the direct cortical response in rat cortex

The electrophysiological basis of epileptiform magnetic fields in neocortex: spontaneous ictal phenomena

Empirical comparison of the MEG and EEG: Animal models of the direct cortical response and epileptiform activity in neocortex

TLDR
The data support the hypothesis that evoked and epileptiform magnetic fields result from intradendritic currents oriented perpendicular to the cortical surface, and provide an empirical foundation for physical models with which to interpret noninvasive neuromagnetic recordings of epileptic discharge in human focal seizure disorders.

Magnetoencephalography in Focal Epilepsy

TLDR
Combined MEG–EEG recordings in conjunction with advanced source modeling techniques should improve the noninvasive evaluation of epilepsy patients and further reduce the need for invasive procedures.

Neuromagnetic investigation of somatotopy of human hand somatosensory cortex

TLDR
It is concluded that SEFs recorded on MEG in conjunction with source localization techniques are useful to investigate functional topography of human hand somatosensory cortex non-invasively.

The relationship between magnetic and electrophysiological responses to complex tactile stimuli

TLDR
The MEG signal is an accurate representation of electrophysiological responses to complex natural stimuli and was better correlated with the LFP than MUA data suggesting that the MEG signals reflects primarily synaptic currents rather than spiking activity.

Magnetoencephalography in presurgical epilepsy evaluation

TLDR
Because MEG and EEG yield both complementary and confirmatory information, combined MEG-EEG recordings in conjunction with advanced source modeling techniques will further improve the noninvasive evaluation of epilepsy patients and constantly reduce the need for invasive procedures.

Controversies in clinical neurophysiology. MEG is superior to EEG in the localization of interictal epileptiform activity: Con

In Vivo Neuromagnetic Study of Normal and Pathological Intracellular Current in Rat Cortex

TLDR
The magnetoencephalogram may be used to localize and study synchronized cellular currents during physiological and pathological cortical activities in animal and man, and may provide valuable information for understanding the neurogenesis of cortical responses.

Neuromagnetic field modeling of multiple brain regions producing interictal spikes in human epilepsy.

References

SHOWING 1-10 OF 24 REFERENCES

Penicillin-induced epileptic phenomena in the rabbit's neocortex I. The development of interictal spikes after epicortical application of penicillin

Penicillin-induced epileptic phenomena in the rabbit's neocortex II. Laminar specific generation of interictal spikes after the application of penicillin to different cortical depths

Electrical sources in human somatosensory cortex: identification by combined magnetic and potential recordings.

TLDR
Fields and potentials occurring 20 to 30 milliseconds after median nerve stimulation in human subjects were compared in order to investigate the sources of evoked potential components that have been attributed by different investigators to the thalamus or thalamocortical afferents, to separate radial sources in somatosensory cortex and motor cortex, or to a tangential source in somatic cortex.

Control mechanisms in cortical epileptogenic foci. "Surround" inhibition.

TLDR
The role of inhibited neurons in a region of focal epileptogenesis and the relationship of such cells to the neuronal population responsible for generation of the surface epileptiform activity is investigated.

Excitatory projection of the rat subicular complex to the cingulate cortex and synaptic integration with thalamic afferents

The penicillin focus. I. Distribution of potential at the cortical surface.

Responses of cortical neurons to stimulation of corpus callosum in vitro.

TLDR
In vitro slice preparation of rat cingulate cortex was used to analyze the responses of layer V neurons to electrical stimulation of the corpus callosum and demonstrated that both pyramidal and nonpyramidal neurons received direct callosal afferents.

Pattern of intracortical potential distribution during focal interictal epileptiform discharges (FIED) and its relation to spinal field potentials in the rat.

On the relation between somatic evoked potentials and fields.

TLDR
A more detailed account of the SEF as well as an analysis of its relation to the SEP and to the somatic pial response (SPR) are described, finding that theSEF recorded normal to the head provides essentially the same information as that provided by reported potential recordings from the exposed surface of the brain (the SPR).

CORTICAL CELLULAR PHENOMENA IN EXPERIMENTAL EPILEPSY: INTERICTAL MANIFESTATIONS.