Intracellular calcium signaling regulates glomerular filtration barrier permeability: the role of the PKGIα-dependent pathway.

@article{Piwkowska2016IntracellularCS,
  title={Intracellular calcium signaling regulates glomerular filtration barrier permeability: the role of the PKGIα-dependent pathway.},
  author={Agnieszka Piwkowska and Dorota Rogacka and Irena Audzeyenka and Małgorzata Kasztan and Stefan Angielski and Maciej Jankowski},
  journal={FEBS letters},
  year={2016},
  volume={590 12},
  pages={1739-48}
}
Podocytes are dynamic polarized cells that lie on the surface of glomerular capillaries and comprise an essential component of the glomerular filtration barrier. Insulin provoked a sustained, approximately 70%, increase in intracellular calcium concentration in podocytes. RT-PCR revealed the presence of mRNA encoding sarco/endoplasmic reticulum calcium… CONTINUE READING