Intracellular calcium levels in phorbol ester-induced contractions of vascular muscle.

@article{Jiang1987IntracellularCL,
  title={Intracellular calcium levels in phorbol ester-induced contractions of vascular muscle.},
  author={M J Jiang and Kathleen G Morgan},
  journal={The American journal of physiology},
  year={1987},
  volume={253 6 Pt 2},
  pages={H1365-71}
}
Intracellular calcium concentration ([Ca2+]i) was measured with aequorin in ferret and rat aortic strips contracted with phorbol esters. In ferret aorta, 12-deoxyphorbol 13-isobutyrate 20-acetate (DPBA, 1 microM) induced contractions without significantly increasing [Ca2+]i, whereas 21 mM K+ induced smaller contractions with a significant rise in [Ca2+]i. Ca2+-free 2.5 mM ethyleneglycol-bis(beta-aminoethylether)-N,N'-tetraacetic acid (EGTA)-physiological saline solution (PSS) had no effect on… CONTINUE READING
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