Intracellular calcium concentration during low-frequency fatigue in isolated single fibers of mouse skeletal muscle.

@article{Westerblad1993IntracellularCC,
  title={Intracellular calcium concentration during low-frequency fatigue in isolated single fibers of mouse skeletal muscle.},
  author={H{\aa}kan Westerblad and Susan Duty and David G. Allen},
  journal={Journal of applied physiology},
  year={1993},
  volume={75 1},
  pages={382-8}
}
Low-frequency fatigue is a form of muscle fatigue that follows intense muscle activity and is characterized by reduced tetanic tension at low frequencies of stimulation while tetanic tension at high stimulus frequencies is close to normal. The present experiments were performed on isolated single fibers of mouse in which tension and intracellular calcium concentration ([Ca2+]i) were measured. Fatigue was produced by intermittent short tetani continued until tension had declined to 30% of… CONTINUE READING
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