Intracellular calcium accumulation during the evolution of hypoxic-ischemic brain damage in the immature rat.

@article{Vannucci1988IntracellularCA,
  title={Intracellular calcium accumulation during the evolution of hypoxic-ischemic brain damage in the immature rat.},
  author={Robert C. Vannucci and Robert M. Brucklacher and Susan J. Vannucci},
  journal={Brain research. Developmental brain research},
  year={1988},
  volume={126 1},
  pages={117-20}
}
An excessive intracellular accumulation of calcium (Ca2+) in neurons and glia has been proposed to represent a major 'final common pathway' for cell death arising from hypoxia-ischemia. To clarify the role of altered calcium flux into the perinatal brain undergoing hypoxic-ischemic damage, 7-day postnatal rats underwent unilateral common carotid artery… CONTINUE READING