Intracellular and extracellular processing of chromogranin A. Determination of cleavage sites.

Abstract

Chromogranins are a family of acidic soluble proteins which exhibit widespread distribution in endocrine cells and neurons. Chromogranin A (CGA), the major soluble component of the secretory granules in chromaffin cells of the adrenal medulla, is a single polypeptide chain of 431 residues with an apparent molecular mass of 70-75 kDa and a pI of 4.5-5. In… (More)

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Cite this paper

@article{MetzBoutigue1993IntracellularAE, title={Intracellular and extracellular processing of chromogranin A. Determination of cleavage sites.}, author={Marie-H{\'e}l{\'e}ne Metz-Boutigue and P Garcia-Sablone and Ruth A. Hogue-Angeletti and Dr. Dominique Aunis}, journal={European journal of biochemistry}, year={1993}, volume={217 1}, pages={247-57} }