Intracellular alkalinization causes Mg2+ release from intracellular binding sites in leech Retzius neurones

@article{Gnzel1997IntracellularAC,
  title={Intracellular alkalinization causes Mg2+ release from intracellular binding sites in leech Retzius neurones},
  author={Dorothee G{\"u}nzel and Simone Durry and Wolf-R{\"u}diger Schlue},
  journal={Pfl{\"u}gers Archiv},
  year={1997},
  volume={435},
  pages={65-73}
}
Abstract Four-barrelled ion-sensitive microelectrodes were developed to enable simultaneous measurement of intracellular free Mg2+ and Na+ concentrations ([Mg2+]i, [Na+]i), intracellular pH and the membrane potential. The electrodes were used to investigate pH-induced [Mg2+]i changes in Retzius neurones of the leech Hirudo medicinalis. The application of propionate or CO2/HCO3–-buffered bath solutions caused a transient intracellular acidification, an initial [Mg2+]i decrease and a continuous… CONTINUE READING
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