Intracellular Staphylococcus aureus escapes the endosome and induces apoptosis in epithelial cells.

@article{Bayles1998IntracellularSA,
  title={Intracellular Staphylococcus aureus escapes the endosome and induces apoptosis in epithelial cells.},
  author={Kenneth W Bayles and C A Wesson and Linda E Liou and L K Fox and Gregory A. Bohach and William R. Trumble},
  journal={Infection and immunity},
  year={1998},
  volume={66 1},
  pages={336-42}
}
We examined the invasion of an established bovine mammary epithelial cell line (MAC-T) by a Staphylococcus aureus mastitis isolate to study the potential role of intracellular survival in the persistence of staphylococcal infections. S. aureus cells displayed dose-dependent invasion of MAC-T cells and intracellular survival. An electron microscopic examination of infected cells indicated that the bacteria induced internalization via a mechanism involving membrane pseudopod formation and then… CONTINUE READING
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