Intracellular Rickettsiales: Insights into manipulators of eukaryotic cells.

@article{Renvois2011IntracellularRI,
  title={Intracellular Rickettsiales: Insights into manipulators of eukaryotic cells.},
  author={Aur{\'e}lie Renvois{\'e} and Vicky Merhej and Kalliopi Georgiades and Didier Raoult},
  journal={Trends in molecular medicine},
  year={2011},
  volume={17 10},
  pages={
          573-83
        }
}
The order Rickettsiales comprises obligate intracellular bacteria that are the ancestors of modern eukaryotes. These bacteria infect various vectors and hosts, with some species being pathogenic to man. Rickettsiales have small, degraded genomes and provide a paradigm for increased pathogenicity despite gene loss; significant levels of genetic exchange occur between bacteria that infect the same host and with the eukaryotic hosts themselves. Crosstalk between host and bacteria appears to be… CONTINUE READING

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