Intracellular Parasite Invasion Strategies

@article{Sibley2004IntracellularPI,
  title={Intracellular Parasite Invasion Strategies},
  author={L. David Sibley},
  journal={Science},
  year={2004},
  volume={304},
  pages={248 - 253}
}
  • L. Sibley
  • Published 9 April 2004
  • Biology
  • Science
Intracellular parasites use various strategies to invade cells and to subvert cellular signaling pathways and, thus, to gain a foothold against host defenses. Efficient cell entry, ability to exploit intracellular niches, and persistence make these parasites treacherous pathogens. Most intracellular parasites gain entry via host-mediated processes, but apicomplexans use a system of adhesion-based motility called “gliding” to actively penetrate host cells. Actin polymerization–dependent motility… 

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