Intracellular PO2 in individual cardiac myocytes in dogs, cats, rabbits, ferrets, and rats.

@article{Gayeski1991IntracellularPI,
  title={Intracellular PO2 in individual cardiac myocytes in dogs, cats, rabbits, ferrets, and rats.},
  author={T E Gayeski and Carl R. Honig},
  journal={The American journal of physiology},
  year={1991},
  volume={260 2 Pt 2},
  pages={H522-31}
}
Myoglobin (Mb) saturation in individual subepicardial myocytes was determined by cryospectroscopy in dogs, cats, ferrets, rabbits, and rats. Mb saturation within 800 microns of the epicardium is not affected by quick freezing or absorption of light by cytochromes. The PO2 in equilibrium with Mb (PMbO2) was calculated from the Mb oxydissociation curve. The minimum PMbO2 found among the 1,000 cells examined was 2.5 Torr, at least five times the critical PO2 for cytochrome turnover in myocardium… CONTINUE READING