[Intracellular Ca2+ behavior and activation of calpain-I in activated platelets].

Abstract

A relationship between intracellular Ca2+ concentration ([Ca2+]i) and calpain-I activation and change in subcellular localization of the enzyme in activated platelets were investigated. The [Ca2+]i exhibited a biphasic response after stimulation with thrombin. Activation of calpain-I was measured by determination of the appearance of active 76 and 78 kDa… (More)

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Cite this paper

@article{Ishii1992IntracellularCB, title={[Intracellular Ca2+ behavior and activation of calpain-I in activated platelets].}, author={Hiromasa Ishii and Yuka Suzuki and Mutsugu Kuboki and Miki Kazama}, journal={Nihon rinsho. Japanese journal of clinical medicine}, year={1992}, volume={50 2}, pages={274-81} }