Intracellular ATP levels affect secondary metabolite production in Streptomyces spp.

@article{Meng2011IntracellularAL,
  title={Intracellular ATP levels affect secondary metabolite production in Streptomyces spp.},
  author={Lingzhu Meng and Ming xia Li and Seung Hwan Yang and Tae-gyun Kim and Joo-won Suh},
  journal={Bioscience, biotechnology, and biochemistry},
  year={2011},
  volume={75 8},
  pages={
          1576-81
        }
}
The addition of extracellular ATP (exATP) to four Streptomyces strains had similar effects: low exATP levels stimulated antibiotic production and high levels reduced it. Compared with antibiotic production, the concentrations of intracellular ATP (inATP) in the tested strains were opposite, which suggests a role of inATP in regulating secondary metabolite production. Under inactivation of the polyphosphate kinase gene (ppk) in Streptomyces lividans, we observed the same results: when the inATP… CONTINUE READING

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SHOWING 1-2 OF 2 REFERENCES

Gene Cloning in Streptomyces’

  • H Hunter
  • Oxford, pp
  • 1995

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