Intracavitary therapy of neoplastic effusions with cytokines: comparison among interferon alpha, beta and interleukin-2.

@article{Lissoni1995IntracavitaryTO,
  title={Intracavitary therapy of neoplastic effusions with cytokines: comparison among interferon alpha, beta and interleukin-2.},
  author={Paolo Lissoni and Sandro Barni and Gabriele Tancini and Antonio Ardizzoia and E. Tisi and Michela Angeli and Anna Rizzi},
  journal={Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer},
  year={1995},
  volume={3 1},
  pages={78-80}
}
Preliminary studies have suggested that the intracavitary administration of cytokines may represent a new effective palliative therapy of malignant effusions. To define further the therapeutic role of cytokines in the treatment of neoplastic fluid accumulation, 70 cancer patients with pleural, pericardial or peritoneal cytologically proven neoplastic effusions were randomized to receive intracavitary cycles with interleukin-2 (IL-2; 6 x 10(6) IU), interferon (IFN alpha; 2 x 10(7) U) or IFN beta… CONTINUE READING

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