Intracavernous Administration of Adipose Stem Cells: A New Technique of Treating Erectile Dysfunction in Diabetic Patient, Preliminary Report of 6 Cases

@inproceedings{Mg2015IntracavernousAO,
  title={Intracavernous Administration of Adipose Stem Cells: A New Technique of Treating Erectile Dysfunction in Diabetic Patient, Preliminary Report of 6 Cases},
  author={Garber Mg and C. Simone nd},
  year={2015}
}
Objectives: After revolutionized treatment of erectile dysfunction (ED) with phosphodiesterase-5 inhibitors (PDE5) inhibitors, approximately 30% of patients are non-responsive. An important cause of this is vascular and smooth muscle dysfunction, as well as nerve atrophy. Stem cells are characterized by anti-inflammatory activities, as well as possibility of differentiating into tissue relevant to the penile architecture, and stimulation of angiogenesis. We report the effects of intracavernosal… 

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References

SHOWING 1-10 OF 26 REFERENCES

The Aetiology and Management of Erectile, Ejaculatory, and Fertility Problems in Men with Diabetes Mellitus

Fertility problems, particularly when associated with ejaculatory failure can be overcome with modern assisted reproductive techniques, and nowadays, these will frequently involve gamete micro‐manipulation.

Type 5 Phosphodiesterase Inhibitors in the Treatment of Erectile Dysfunction and Cardiovascular Disease

The U.S. Food and Drug Administration approved sildenafil as an orally active therapy for the treatment of primary pulmonary hypertension and the drug will be marketed under the trade name of Revatio, not Viagra, the name used for the ED indication.

Recent advances in andrology-related stem cell research.

Evidence is shown that ESC could restore the erectile function of neurogenic ED in rats, and there is evidence that ADSC could do so as well, and whether ADSC can differentiate into Leydig, Sertoli and male germ cells is investigated.

Nitric oxide and penile erectile function.

Evaluation and nonsurgical management of erectile dysfunction.

  • I. Sharlip
  • Medicine, Psychology
    The Urologic clinics of North America
  • 1998

Cell‐Assisted Lipotransfer for Facial Lipoatrophy: Efficacy of Clinical Use of Adipose‐Derived Stem Cells

The results suggest that cell-assisted lipotransfer (CAL) is both effective and safe and potentially superior to conventional lipoinjection for facial recontouring.

Systemic delivery of umbilical cord blood cells for stroke therapy: a review.

A growing number of studies highlight the potential of systemic delivery of H UCB cells as a novel therapeutic approach for stroke, however, additional preclinical studies are warranted to reveal the optimal HUCB transplant regimen that is safe and efficacious prior to proceeding to large-scale clinical application of these cells for stroke therapy.

Human neural crest stem cells transplanted in rat penile corpus cavernosum to repair erectile dysfunction

To investigate the feasibility of applying neural crest stem cells (NCSCs), with multipotent capacity, to repair injury in the penile cavernosum, the HNC10.K10 (K10) immortalized NCSC line was transplanted into thePenile cavernous smooth muscle cells and sinus endothelial cells.

Infusion of Mesenchymal Stem Cells Ameliorates Hyperglycemia in Type 2 Diabetic Rats

Data indicate that multiple roles and mechanisms are involved in the efficacy of MSCs in ameliorating hyperglycemia in rats with type 2 diabetes (T2D) and improving insulin sensitivity in T2D.