Intrabolus pressure gradient identifies pathological constriction in the upper esophageal sphincter during flow.

@article{Pal2003IntrabolusPG,
  title={Intrabolus pressure gradient identifies pathological constriction in the upper esophageal sphincter during flow.},
  author={Anupam Pal and Rohan B. H. Williams and Ian Cook and James G Brasseur},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2003},
  volume={285 5},
  pages={G1037-48}
}
Propulsion of a bolus through the upper esophageal sphincter (UES) is driven by a pressure drop in the direction of flow against frictional resisting force. Basic mechanics suggest that the axial rate of drop in intrabolus pressure (IBP), i.e., the intrabolus pressure gradient (IBPG), should be locally sensitive to abnormal constriction. We sought to quantify space-time patterns of IBP and IBPG that correlate with pathological disruption to transsphincteric bolus transport. High-resolution high… CONTINUE READING