Intraarticular, epidural, and intravenous analgesia after total knee arthroplasty.

  title={Intraarticular, epidural, and intravenous analgesia after total knee arthroplasty.},
  author={J. Klasen and Stefan Opitz and Charlotte Melzer and Andreas Thiel and Gunter Hempelmann},
  journal={Acta anaesthesiologica Scandinavica},
  volume={43 10},
BACKGROUND After total knee arthroplasty, patients regularly suffer from severe pain. It is unclear whether epidural or systemic pain therapy is superior in terms of postoperative pain relief, patients' comfort and side effects. A new therapeutic approach, intraarticular opioids, has been suggested with the detection of opioid receptors in inflamed tissue. This method has proven suitable for clinical use in small operations (e.g. knee arthroscopy). In this study, we compared epidural analgesia… CONTINUE READING


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