Intraarterial catheter-directed thrombolysis: urokinase versus tissue plasminogen activator.

@article{Cin1999IntraarterialCT,
  title={Intraarterial catheter-directed thrombolysis: urokinase versus tissue plasminogen activator.},
  author={Claudio Salvatore Cin{\`a} and Robbie B. H. Goh and J K H Chan and Brendan Kenny and Gregory J Evans and John Rawlinson and Gerry Gill},
  journal={Annals of vascular surgery},
  year={1999},
  volume={13 6},
  pages={571-5}
}
The purpose of this study was to evaluate the differences between tissue plasminogen activator (TPA) and urokinase (UK) in the management of ischemic limbs. A total of 58 limbs (24 in the TPA group and 34 in the UK group) in 53 patients were studied prospectively. The two groups were based on the surgeon's preference for lytic agent. The dose regimen for UK was 150,000 IU/hr over 1/2 to 2 hr followed by a continuous infusion of 50,000 IU/hr. TPA was given as a 5-mg bolus followed by 1 mg/hr… CONTINUE READING

From This Paper

Topics from this paper.