Intra-operative activation of coagulation--a stimulus to thrombosis mediated by vasopressin?

@article{Grant1986IntraoperativeAO,
  title={Intra-operative activation of coagulation--a stimulus to thrombosis mediated by vasopressin?},
  author={PeterJ. Grant and Glenda Tate and Jacquita A. Davies and Nicola Williams and ColinR.M. Prentice},
  journal={Thrombosis and haemostasis},
  year={1986},
  volume={55 1},
  pages={
          104-7
        }
}
Vasopressin infusions in normal volunteers that produce concentrations in plasma comparable to those seen during stress, cause an increase in plasma factor VIII and shortening of the euglobulin clot lysis time (ECLT). We have investigated the relationship between endogenous vasopressin (aVP) release and haemostatic function in 7 patients undergoing major abdominal surgery. Blood samples were taken at nine intervals during the operative procedure. Plasma aVP levels peaked at median values of 51… CONTINUE READING
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