Intra-molecular G-quadruplex structure generated by DNA-templated click chemistry: "turn-on" fluorescent probe for copper ions.

Abstract

A novel homogenous fluorescent sensor for signal-on detection of Cu(2+) has been developed based on intra-molecular G-quadruplex formed by DNA-templated click reaction and crystal violet (CV) as label-free signal reporter. The clickable DNA probe consists of two G-rich strands (A and B) bearing azide and alkyne group, respectively, and a template strand (C… (More)
DOI: 10.1016/j.bios.2013.12.019

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