Intra-median raphe nucleus (MRN) infusions of muscimol, a GABA-A receptor agonist, reinstate alcohol seeking in rats: role of impulsivity and reward

@article{Dzung2007IntramedianRN,
  title={Intra-median raphe nucleus (MRN) infusions of muscimol, a GABA-A receptor agonist, reinstate alcohol seeking in rats: role of impulsivity and reward},
  author={Anh L{\^e} Dzung and Douglas Funk and Stephen Harding and Walter Juzytsch and Zhaoxia Li and Paul N. Fletcher},
  journal={Psychopharmacology},
  year={2007},
  volume={195},
  pages={605-615}
}
We previously found that the inhibition of median raphe nucleus (MRN) 5-HT transmission by local injections of a 5-HT1A agonist 8-OH-DPAT or corticotrophin-releasing factor (CRF) mimic the effect of foot shock stress to reinstate alcohol seeking. In this study, we further explored the role of the MRN by examining the effect of inhibition of MRN neurons, by injecting the GABA-A receptor agonist muscimol, on the reinstatement of alcohol seeking. Male rats were trained to lever press for 12… CONTINUE READING
0 Extracted Citations
38 Extracted References
Similar Papers

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 38 references

The rat brain in stereotaxic coordinates

  • G Paxinos, C Watson
  • 4th edn. Academic,
  • 1998
Highly Influential
2 Excerpts

Similar Papers

Loading similar papers…