Intra-articular hyaluronan injections for the treatment of osteoarthritis of the knee: a randomized, double blind, placebo controlled study.

@article{Tamir2001IntraarticularHI,
  title={Intra-articular hyaluronan injections for the treatment of osteoarthritis of the knee: a randomized, double blind, placebo controlled study.},
  author={Eran Tamir and David Robinson and Rumelia Koren and Gavriel Agar and Nahum Halperin},
  journal={Clinical and experimental rheumatology},
  year={2001},
  volume={19 3},
  pages={265-70}
}
OBJECTIVE Hyaluronic acid (HA) polymers have been found to be useful as viscosupplements for the treatment of osteoarthritis (OA) in a number of clinical studies. It appears that HA with high molecular weights (HMW) are more effective than low molecular weight HA polymers. METHODS A single blind, initial randomized study was conducted involving two randomly selected patient groups, which received injections of either placebo or BioHy, a highly purified HMW HA produced by bacterial… CONTINUE READING

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