Intra-articular Injected synovial stem cells differentiate into meniscal cells directly and promote meniscal regeneration without mobilization to distant organs in rat massive meniscal defect.

@article{Horie2009IntraarticularIS,
  title={Intra-articular Injected synovial stem cells differentiate into meniscal cells directly and promote meniscal regeneration without mobilization to distant organs in rat massive meniscal defect.},
  author={Masafumi Horie and Ichiro Sekiya and Takeshi Muneta and Shizuko Ichinose and Kenji Matsumoto and Hirohisa Saito and Takashi Murakami and Eiji Kobayashi},
  journal={Stem cells},
  year={2009},
  volume={27 4},
  pages={878-87}
}
Osteoarthritis in the knees, which can be caused by meniscal defect, constitutes an increasingly common medical problem. Repair for massive meniscal defect remains a challenge owing to a lack of cell kinetics for the menisci precursors in knee joint. The synovium plays pivotal roles during the natural course of meniscal healing and contains mesenchymal stem cells (MSCs) with high chondrogenic potential. Here, we investigated whether intra-articular injected synovium-MSCs enhanced meniscal… CONTINUE READING
92 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 92 extracted citations

Similar Papers

Loading similar papers…