Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism.

@article{Furlan1999IntraarterialPF,
  title={Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism.},
  author={Anthony J. Furlan and Randall Higashida and Lawrence R. Wechsler and Michael J. Gent and Howard D Rowley and Carlos S. Kase and Michael S. Pessin and Anil Ahuja and Fred Callahan and Wayne M. Clark and Frank Silver and F Rivera},
  journal={JAMA},
  year={1999},
  volume={282 21},
  pages={2003-11}
}
CONTEXT Intravenous tissue-type plasminogen activator can be beneficial to some patients when given within 3 hours of stroke onset, but many patients present later after stroke onset and alternative treatments are needed. OBJECTIVE To determine the clinical efficacy and safety of intra-arterial (IA) recombinant prourokinase (r-proUK) in patients with acute stroke of less than 6 hours' duration caused by middle cerebral artery (MCA) occlusion. DESIGN PROACT II (Prolyse in Acute Cerebral… CONTINUE READING
Highly Influential
This paper has highly influenced 58 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
1,053 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 1,053 extracted citations

Similar Papers

Loading similar papers…