Intra- and interindividual epigenetic variation in human germ cells.

@article{Flanagan2006IntraAI,
  title={Intra- and interindividual epigenetic variation in human germ cells.},
  author={James M Flanagan and Violeta Popendikyte and Natalija Pozdniakovaite and Martha Sobolev and Abbas Assadzadeh and Axel Schumacher and Masood Zangeneh and Lynette Lau and Carl Virtanen and Sun-Chong Wang and Artūras Petronis},
  journal={American journal of human genetics},
  year={2006},
  volume={79 1},
  pages={
          67-84
        }
}
Epigenetics represents a secondary inheritance system that has been poorly investigated in human biology. The objective of this study was to perform a comprehensive analysis of DNA methylation variation between and within the germlines of normal males. First, methylated cytosines were mapped using bisulphite modification-based sequencing in the promoter regions of the following disease genes: presenilins (PSEN1 and PSEN2), breast cancer (BRCA1 and BRCA2), myotonic dystrophy (DM1), and… 

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