Intra- and extracellular events in luminol-dependent chemiluminescence of polymorphonuclear leukocytes.

@article{Briheim1984IntraAE,
  title={Intra- and extracellular events in luminol-dependent chemiluminescence of polymorphonuclear leukocytes.},
  author={Gunnar Briheim and Olle Stendahl and Claes Dahlgren},
  journal={Infection and immunity},
  year={1984},
  volume={45 1},
  pages={
          1-5
        }
}
When polymorphonuclear leukocytes (PMNL) and soluble or particulate matter interact, the cells produce chemiluminescence. Luminol-dependent light emission from PMNL is linked to the myeloperoxidase (MPO)-H2O2 system. Light emission from a cell-free MPO-H2O2 system was found to be totally inhibited by human serum albumin (HSA), and since HSA is a large molecular protein that does not readily gain access to intracellular sites of PMNL, it could be used to determine the importance of extra- and… CONTINUE READING

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Effect of in vitro preincubation of polymorphonuclear leukocytes on formymethionylleucyl-phenylalanine-induced chemiluminescence

  • C. Dahlgren
  • Stendahl
  • 1982
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