Intra- and Interspecific Variation in Primate Gene Expression Patterns

@article{Enard2002IntraAI,
  title={Intra- and Interspecific Variation in Primate Gene Expression Patterns},
  author={W. Enard and P. Khaitovich and J. Klose and S. Z{\"o}llner and F. Heissig and P. Giavalisco and K. Nieselt-Struwe and E. Muchmore and A. Varki and R. Ravid and G. Doxiadis and R. Bontrop and S. P{\"a}{\"a}bo},
  journal={Science},
  year={2002},
  volume={296},
  pages={340 - 343}
}
Although humans and their closest evolutionary relatives, the chimpanzees, are 98.7% identical in their genomic DNA sequences, they differ in many morphological, behavioral, and cognitive aspects. The underlying genetic basis of many of these differences may be altered gene expression. We have compared the transcriptome in blood leukocytes, liver, and brain of humans, chimpanzees, orangutans, and macaques using microarrays, as well as protein expression patterns of humans and chimpanzees using… Expand
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