Intra-accumbens shell injections of SR48692 enhanced cocaine self-administration intake in rats exposed to an environmentally-elicited reinstatement paradigm.

@article{RamosOrtolaza2009IntraaccumbensSI,
  title={Intra-accumbens shell injections of SR48692 enhanced cocaine self-administration intake in rats exposed to an environmentally-elicited reinstatement paradigm.},
  author={Dinah Lee Ramos-Ortolaza and Alejandro Negr{\'o}n and Daryana Cruz and Edgardo Falc{\'o}n and Mari Carmen Iturbe and Mariela Hern{\'a}ndez Cajigas and Carmen S. Maldonado-Vlaar},
  journal={Brain research},
  year={2009},
  volume={1280},
  pages={124-36}
}
Neurotensin (NT) is a neuropeptide involved in cocaine reward, and in learning and memory processes related to drug use within the mesolimbic dopamine (DA) system. Studies have demonstrated that NT receptor antagonists have potential as pharmacotherapeutical tools for cocaine abuse. Therefore, it is important to understand the molecular profile of NT within mesolimbic neurons and the behavioral effects of NT receptor inhibitors on environmentally-elicited cocaine seeking behavior. To address… CONTINUE READING

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