Intolerance of folic acid in a patient receiving methotrexate for Crohn's disease.

@article{Katsanos2012IntoleranceOF,
  title={Intolerance of folic acid in a patient receiving methotrexate for Crohn's disease.},
  author={Konstantinos H. Katsanos and Vasileios Tsianos and Epameinondas Tsianos},
  journal={Journal of Crohn's & colitis},
  year={2012},
  volume={6 9},
  pages={960}
}
Folic and folinic acid supplementation have been shown to reduce methotrexate oral and gastrointestinal side effects in rheumatoid arthritis patients1 and this seems to be also the case in patients with inflammatory bowel disease. Still, it is not clear whether folic is different from folinic acid in reducing methotrexate gastrointestinal side effects.2 We present herein a patient with a “difficult-to-treat” long-standing Crohn's disease who was diagnosed with gastrointestinal intolerance due… CONTINUE READING