Intimate details of the most poisonous poison

  title={Intimate details of the most poisonous poison},
  author={Bal Ram Singh},
  journal={Nature Structural Biology},
Crystal structures of type B botulinum neurotoxin, determined under conditions relevant to the extracellular binding and intracellular substrate cleavage steps of its toxic action, reveal that minimal structural changes occur upon binding a ganglioside or after substrate cleavage. The unique structure of this toxin provides information for developing preventive measures against botulism. 
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