Intimal thickening and medial necrosis in allograft arteriosclerosis (chronic rejection) are independently regulated.

Abstract

Rat aortic allografts from the DA (RT1a) to the WF (RT1v) strain but not syngeneic DA-to-DA control grafts develop arteriosclerotic changes in the vascular wall that are virtually identical to human allografts during chronic rejection. A more prominent medial cell destruction in the rat aorta, leading ultimately to complete medial necrosis, is the major… (More)

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Cite this paper

@article{Mennander1993IntimalTA, title={Intimal thickening and medial necrosis in allograft arteriosclerosis (chronic rejection) are independently regulated.}, author={Ari Adolf Mennander and Timo Paavonen and Pekka J H{\"a}yry}, journal={Arteriosclerosis and thrombosis : a journal of vascular biology}, year={1993}, volume={13 7}, pages={1019-25} }