Intestinal venous drainage through the liver is a prerequisite for oral tolerance induction.

@article{Yang1994IntestinalVD,
  title={Intestinal venous drainage through the liver is a prerequisite for oral tolerance induction.},
  author={R. Q. Yang and Qi Liu and Jay L. Grosfeld and Mark D. Pescovitz},
  journal={Journal of pediatric surgery},
  year={1994},
  volume={29 8},
  pages={1145-8}
}
One feature of enteric mucosal immunity is oral tolerance (OT), a state of diminished systemic immune responsiveness to an antigen induced by previous oral feeding of that antigen. Because OT induction requires an interaction between the intestinal and systemic immune systems, the authors plan to use it as a method in experimental small bowel transplantation (SBT) to evaluate the ability of the intestinal allograft to cooperate immunologically with the host. Two different methods have been used… CONTINUE READING
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