Intestinal tumorigenesis in Min mice is enhanced by X-irradiation in an age-dependent manner.

@article{Okamoto2005IntestinalTI,
  title={Intestinal tumorigenesis in Min mice is enhanced by X-irradiation in an age-dependent manner.},
  author={Mieko Okamoto and Hiromichi Yonekawa},
  journal={Journal of radiation research},
  year={2005},
  volume={46 1},
  pages={83-91}
}
We examined the effect of X-irradiation on intestinal tumorigenesis in Min (multiple intestinal neoplasia) mice. Single whole-body irradiation was given to mice of various ages from newborn to young adults. On the C57BL/6J (B6) background, X-irradiation increased tumor multiplicity of the small intestine exposed at ages from 2-3 days to 24-25 days, with a peak of 2.7-fold increase at 10-12 days of age; exposure at later ages resulted in only a slight increase. X-irradiation also increased… CONTINUE READING
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