Intestinal smooth muscle phenotype determines enteric neuronal survival via GDNF expression.

Abstract

Intestinal inflammation causes initial axonal degeneration and neuronal death, as well as the proliferation of intestinal smooth muscle cells (ISMC), but subsequent axonal outgrowth leads to re-innervation. We recently showed that expression of glial cell-derived neurotrophic factor (GDNF), the critical neurotrophin for the post-natal enteric nervous system… (More)
DOI: 10.1016/j.neuroscience.2015.01.056

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